About the IIIDB

Nowadays, many protein-protein interaction (PPI) databases are available, but the isoform level PPI prediction database has not been seen yet. Thus, we developed the first isoform-isoform interaction database, IIIDB (http://syslab.nchu.edu.tw/IIIDB). The interactions in IIIDB were calculated by a logistic regression approach that integrates information from RNA-seq datasets and domain-domain interaction.


Upload your gene expression data


The first column is RefSeq id (e.g., NM_XXXXXX) and the following columns are fpkm values of gene expression.
Data Formats:
For gene expression data import, IIIDB operates with basic text-base formats such as CSV and TXT format, where data items are separated by delimiters (e.g., spaces, tabs or commas).
Example file can be downloaded from here.

Upload your gene expression data


Interaction Search (High-confidence prediction, score > 2.575)


e.g. BCL2L1 or 598


Interaction Search (Low-confidence prediction, score > 1.692)


e.g. BCL2L1 or 598


Module Search

e.g. BCL2L1 or 598